Lisa would go on lurking through the catacombs of Spencer’s estate, secretly claiming residency in a neglected cabin. However, Umbrella did not realize that the experiments conducted on her had ironically enough left her impervious to almost all forms of battery, having little to no effect on the crawling abomination.
Sometime in 1995, Lisa was supposedly slain in an undisclosed area of Spencer’s estate. As Lisa was now seen a vestigial threat, Umbrella officials called for Lisa’s immediate termination. On one occasion, she brutally assaulted and killed three lab researchers. As time passed, Lisa’s mutations and isolation from her mother led her to become increasingly violent. Ultimately, this was a major breakthrough for the Umbrella Corporation, that would later go on to play a pivotal role in the engineering of the G-Virus.Īfter the G-Virus was extracted from Lisa, the Umbrella Corporation lost interest in her. To their astonishment, Lisa not only overcame the specimen, but also managed to absorb it and adapt its powers into her system. This uncanny immunity earned the attention of Umbrella Corporation researchers, Albert Wesker and William Birkin, who injected their formidable guinea pig with a specimen of the Nemesis parasite. Unlike her fellow, more fortunate test subjects, Lisa was able to survive all of their tests, regardless of the potency of the implanted virus or parasite. Lisa served as a test subject for many years. Lisa, thinking that the look-alike's face was actually stolen from her real mother, ripped it off of the imposter and promised to return it to Jessica when they were together again. But Lisa was unable to be fooled, despite the fake's physical resemblance to Jessica. To placate Lisa, Umbrella placed an impersonator to act as her mother. After receiving her mother's letter, she became distressed when Jessica was nowhere to be found, wondering if her mother had already left without her. While in the facility, Lisa developed a strong need to reunite with her parents. On the other hand, Lisa was put under protected observation due to the successful results with the virus, and became a canvas for further experimentation. Unfortunately, Jessica was later disposed of by Spencer's forces, as she was no longer of interest due to her negative results for fusion of the Progenitor virus. Jessica wrote a letter to her daughter, planning an escape from the research facility. Over a period of time, both Lisa’s mental and physical state were grotesquely altered. Jessica’s bodily systems were able to fight off the virus, while Lisa body immediately began to exhibit signs of mutation. On November 10, 1967, Lisa was administered the "B-Type" variation of the Progenitor virus, while Jessica was administered the "A-Type" variation. While George was writhing in his eternal resting place, Lisa and Jessica were kidnapped by Spencer’s henchmen, and used as human test subjects for the Progenitor virus. Instead of being done away with immediately, George was thrown into a secret compartment of the mansion, and endured a subtle and lonely demise. Spencer eventually became paranoid that George would someday leak the mansion's secrets to the public, and ordered his henchmen to apprehend and execute George. Spencer hired George to design a special mansion complex for him in the Arklay Mountains, which would also host a secret underground laboratory. Lisa was born to Jessica and George Trevor in 1953. When attacked, numerous tentacles fly out and spasm from her body, a sign of the NE-Alpha parasite used to create the Nemesis Tyrant.
Lisa is able to deal considerable amounts of damage to her victims, and should not be confronted directly, as no weapons can truly stop her. She also is able to croak " Mo.ther." upon finding her mother's skull. However, it should be noted that Lisa was able to start a fire in order to warm herself, as well as write a few crude entries in her journal. This characteristic suggests that Lisa is incapable of utilizing a higher level of thought process, and therefore conforms to a more animalistic nature. While in various parts of the Spencer Estate, one may hear the harrowing wails and cries of Lisa. There is also a eyeball-like tumor visable on her back, a typical sign of the G-virus. Furthermore, Lisa is draped in a tattered hospital gown, and chained to a pair of wooden stocks lined with iron, which act as a deterrent to Lisa's attacks. Her oversized arms and hunched back resemble the body build of an orangutan. During some cut-scenes, one may be able to notice one of Lisa’s uncanny eyes through a small hole in her mask. Lisa’s face is partially masked by collections of flesh from her victim. Lisa’s mutations have hideously distorted her physical build.